the association between proinflammatory gene polymorphisms and level of gingival tissue degradation in chronic periodontitis
نویسندگان
چکیده
منابع مشابه
The association between selected RANKL gene polymorphisms and chronic/aggressive periodontitis in Iranian subjects
The primary aim of this study was to investigate the status of RANKL6-7 gene polymorphism in patients with chronic (mild, moderate, severe) and aggressive periodontitis as well as healthy controls. We examined80 patients for the RANKL6-7 polymorphisms (rs1054016 and rs9567000). Polymorphism was determinedby polymerase chain reaction (PCR) followed by direct sequencing. No statistica...
متن کاملassociation between tgf-beta1 (-509) c/t gene polymorphism and tissue degradation level in chronic periodontitis: a stereological study
conclusions the results of the present study showed that tgf-β1 (-509) c/t is strongly associated with quantitative parameters of connective tissue constituents of interdental papilla in cp patients. results the volume density (vʋ) of epithelium, connective tissue, collagenous and non-collagenous matrix and blood vessels had statistically significant differences between the control and chronic ...
متن کاملClinical Relevance of Cytokines Gene Polymorphisms and Protein Levels in Gingival Cervical Fluid from Chronic Periodontitis Patients
Background: Cytokines are suggested to play a role in periodontitis. Objective: To determine and compare the levels of Interleukin-1 beta (IL-1β) and Tumor necrosis factor alpha (TNF-α) in gingival crevicular fluid (GCF) samples amongst healthy individuals and those with chronic periodontitis. Further to compare the GCF cytokine levels in three genotype classes defined by the respective gene p...
متن کاملAssociation between TGF-Beta1 (-509) C/T Gene Polymorphism and Tissue Degradation Level In Chronic Periodontitis: A Stereological Study
Background: The recent years has seen enormous research attempts in the study for genetic factors that may predispose individuals to periodontitis, as one of the most common chronic infectious disease in humans. Objectives: The aim of the present study was to determine the breakdown of interdental gingiva tissues in chronic periodontitis patients with TGF-β1 (-509) C/T polymorphisms. Patients a...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولGene Polymorphisms in Chronic Periodontitis
We aimed to conduct a review of the literature for gene polymorphisms associated with chronic periodontitis (CP) susceptibility. A comprehensive search of the literature in English was performed using the keywords: periodontitis, periodontal disease, combined with the words genes, mutation, or polymorphism. Candidate gene polymorphism studies with a case-control design and reported genotype fre...
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عنوان ژورنال:
gene, cell and tissueجلد ۱، شماره ۲، صفحات ۰-۰
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